Description
KPV (Lys-Pro-Val) is a naturally occurring tripeptide fragment corresponding to the C-terminal sequence of alpha-melanocyte-stimulating hormone (α-MSH). It is supplied by NovaLife Science Laboratories as a lyophilized powder at 10 mg per vial, independently verified for 99%+ purity via HPLC by a certified third-party laboratory.
Compound Overview
KPV retains certain biological activity properties associated with the parent α-MSH peptide, making it the subject of ongoing research into inflammatory response modulation, intestinal barrier integrity, and cellular homeostasis. Its compact tripeptide structure (Lysine-Proline-Valine) confers favorable stability characteristics and resistance to enzymatic degradation relative to full-length α-MSH.
Current published research has examined KPV’s interactions with melanocortin receptors, particularly MC1R and MC3R, as well as its downstream effects on pro-inflammatory cytokine signaling pathways including NF-κB and MAPK cascades. The compound is frequently used in in-vitro models studying intestinal inflammation and epithelial cell biology.
Analytical Specifications
| Form | Lyophilized Powder |
|---|---|
| Net Weight | 10 mg |
| Purity | 99%+ (HPLC Verified) |
| Sequence | Lys-Pro-Val (C-terminal α-MSH fragment) |
| Source | Synthetic |
| Storage | Store refrigerated 2–8°C. Do not freeze. |
| Testing | Independent third-party HPLC + Mass Spectrometry |
Reconstitution
Reconstitute with bacteriostatic water or physiological saline (0.9% NaCl). Allow the vial to equilibrate to room temperature before opening. Add solvent slowly against the vial wall and swirl gently — do not vortex. See our Laboratory Resources page for full reconstitution and storage protocols.
Research Use Only
For laboratory research use only. Not for human or veterinary use. Not intended to diagnose, treat, cure, or prevent any disease. Purchasers must be 18+ and confirm research use at checkout.
